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How to Open a Dispensary in Minnesota in 2025

They say if you do what you love, you’ll never work a day in your life. While running a dispensary is no small feat, for cannabis enthusiasts in Minnesota, it can be a highly rewarding business venture.

If you’re exploring how to open a dispensary in Minnesota, you’ve likely realized that success requires more than passion. You’ll need a prime location, high-quality cannabis products, a reliable point-of-sale (POS) system, a skilled team, and—most importantly—a cannabis retail license from the state of Minnesota. But what does it actually cost to get started?

Startup Costs for a Cannabis Dispensary in Minnesota

Opening a dispensary is generally more expensive than starting most other small businesses. In Minnesota, upfront costs typically range between $380,000 and $420,000, depending on the location, size, and specific facility requirements. This includes:

  • Staffing: Around $250,000 annually for trained budtenders, supervisors, and managers.
  • Real Estate & Renovations: Expect $100,000 for annual rent plus $50,000 for initial renovations, interior design, and regulatory compliance.
  • Inventory: Stocking high-quality cannabis products can cost approximately $1,600 per pound.
  • Equipment & Technology: POS systems, security cameras, and other business equipment may total around $25,000.

Licensing Fees in Minnesota

Before you even open your doors, Minnesota requires a cannabis retail application fee of $2,500, an initial licensing fee of $2,500, and an annual license renewal fee of $5,000. These fees ensure your dispensary is fully compliant with state regulations.

Real Estate Considerations

Finding the right location in Minnesota is crucial. Zoning laws strictly regulate how close dispensaries can be to schools, parks, or other sensitive areas. Commercial real estate prices vary widely:

  • Average cost per square foot: $216
  • Maximum cost per square foot: $2,684
  • Average rental rates in Minneapolis: $32 per sq ft
  • Average rental rates in St. Paul: $24 per sq ft

Upfront remodeling costs to meet regulations and create an optimal store layout can run around $50,000.

Banking and Financial Management

Because cannabis is federally illegal, many traditional banks may not work with dispensaries. Minnesota dispensary owners often rely on cannabis-friendly credit unions or private banking institutions, which can charge up to $2,000 per month in holding or service fees.

Ongoing Operational Expenses

After licensing and setup, your ongoing monthly costs in Minnesota may range from $25,000 to $75,000, depending on staffing, rent, inventory, and marketing. Other key operational expenses include:

  • Advertising: $25,000 annually (depending on competition and reach)
  • Legal and Insurance: Around $4,000 per year for an attorney and comprehensive insurance policy

Comparing Minnesota Dispensary Costs with Other States

For context, opening a dispensary in Minnesota is moderately priced compared to other states:

  • California: $80,000–$250,000 upfront
  • New York: $500,000–$1 million
  • Oklahoma: $80,000–$140,000

Minnesota’s costs are higher than some low-cost states but lower than high-demand markets like California or New York.

Potential Revenue and Profitability

How much you can earn as a Minnesota dispensary owner depends on your location, market competition, and operational efficiency. A well-run dispensary in a high-demand area can generate substantial revenue, but careful planning and budgeting are key.

Final Thoughts

Opening a dispensary in Minnesota requires a significant upfront investment, careful planning, and a deep understanding of regulatory compliance.

Expect initial costs between $380,000 and $420,000, with ongoing monthly expenses of $25,000–$75,000.

With the right strategy, a well-selected location, and dedicated staff, your Minnesota dispensary can be a profitable and fulfilling business.

Looking for more insights on how to open a dispensary in Minnesota? Download our free guide for step-by-step tips, cost breakdowns, and expert strategies to help you succeed.

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